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- Feb 24, 2013
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I need certain things defined in the Reproductive system.
Basically, they are Leydig cells, Sertoli Cells, Granulosa Cells, Theca Cells, LH, FSH, Progesterone, and Estrogen. I need to connect them all somehow and I'm having trouble doing that. Here is what I have. PLEASE correct me and add to what I need to know.
Theca Cells- In female reproductive system, theca cells are activated by LH to make them secrete testosterone (androgen) into the follicle.
Granulosa Cells- Also called follicle cells. These are stimulated by FSH and convert the secreted androgen into estrogen. This promotes the primary oocyte which is stuck in meiosis I at prophase to progress through meiosis and form the secondary oocyte which is stopped at metaphase II. Granulosa cells nurture the oocyte.
Leydig cells- In males, these are activated by LH and secrete testosterone in the interstitium and Sertoli cells.
Sertoli cells- nurture the primary spermatocyte and are activated by FSH. These convert the testosterone into hydroxytestosterone which promotes......I guess meiosis II of secondary spermatocyte to spermatids???
LH- What is the primary role of this?? I know these are activated by GNRH and act on the follicle. LH increases during the luteal phase. It is inhibited by estrogen and progesterone during the menstrual phase (beginning) but right before ovulation (proliferative phase), it is promoted by estrogen. I also know that LH is responsible for maintaining the corpus luteum before the blastocyte can secrete HCG hormone (so corpus luteum keeps secreting progesterone)
FSH- I don't know much about this, but I know its activated by GNRH, acts on Sertoli and Granulosa cells to convert androgens. What else should I know? I guess it increases during proliferative phase along with LH.
I have a lot of info but am having trouble painting a complete picture here!
Basically, they are Leydig cells, Sertoli Cells, Granulosa Cells, Theca Cells, LH, FSH, Progesterone, and Estrogen. I need to connect them all somehow and I'm having trouble doing that. Here is what I have. PLEASE correct me and add to what I need to know.
Theca Cells- In female reproductive system, theca cells are activated by LH to make them secrete testosterone (androgen) into the follicle.
Granulosa Cells- Also called follicle cells. These are stimulated by FSH and convert the secreted androgen into estrogen. This promotes the primary oocyte which is stuck in meiosis I at prophase to progress through meiosis and form the secondary oocyte which is stopped at metaphase II. Granulosa cells nurture the oocyte.
Leydig cells- In males, these are activated by LH and secrete testosterone in the interstitium and Sertoli cells.
Sertoli cells- nurture the primary spermatocyte and are activated by FSH. These convert the testosterone into hydroxytestosterone which promotes......I guess meiosis II of secondary spermatocyte to spermatids???
LH- What is the primary role of this?? I know these are activated by GNRH and act on the follicle. LH increases during the luteal phase. It is inhibited by estrogen and progesterone during the menstrual phase (beginning) but right before ovulation (proliferative phase), it is promoted by estrogen. I also know that LH is responsible for maintaining the corpus luteum before the blastocyte can secrete HCG hormone (so corpus luteum keeps secreting progesterone)
FSH- I don't know much about this, but I know its activated by GNRH, acts on Sertoli and Granulosa cells to convert androgens. What else should I know? I guess it increases during proliferative phase along with LH.
I have a lot of info but am having trouble painting a complete picture here!
