Can someone explain this question?

[mariposas905]

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I don't understand this...how is it that C is correct? We are talking about an exon, not an intron...

 

[chaim123]

I don't understand this...how is it that C is correct? We are talking about an exon, not an intron...

The terminal G of a 5' exon is the place where the hydroxyl attacks to begin the process of intron splicing. If that G is mutated to something else, no hydroxyl attack will occur, and then intron located after that position will never be spliced away.

 

[mariposas905]

The terminal G of a 5' exon is the place where the hydroxyl attacks to begin the process of intron splicing. If that G is mutated to something else, no hydroxyl attack will occur, and then intron located after that position will never be spliced away.

Oh okay, thanks! Was this in the Kaplan biochemistry chapter? I didn't know this fact 😕 and does that mean all the exons have G in them?

 

[chaim123]

Oh okay, thanks! Was this in the Kaplan biochemistry chapter? I didn't know this fact 😕 and does that mean all the exons have G in them?

Honestly - I've never heard this fact before. Did fine on the MCAT. Heading to medical school. I guess now you know.