Can you take these meds at the same time?

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Pharm0307

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Is there a resource that you guys use to know whether it's ok to take certain meds at the same time? I've typically been saying it's ok while on my rotation unless I know of a specific interaction or if both meds have a similar side effect that could be intensified if taken simultaneously (ACE-inhibitor and beta blocker could both cause dizziness) and the patient hasn't taken them before and therefore doesn't know just how they will react.
 
Is there a resource that you guys use to know whether it's ok to take certain meds at the same time? I've typically been saying it's ok while on my rotation unless I know of a specific interaction or if both meds have a similar side effect that could be intensified if taken simultaneously (ACE-inhibitor and beta blocker could both cause dizziness) and the patient hasn't taken them before and therefore doesn't know just how they will react.


Do you tell people not to take ACEI and BB together, then?
 
No, I would tell them that it is okay to take both an ACE-I and a BB simultaneously. But for instance, the other day we had a patient who was taking Levitra and got a new script for doxazosin, and an DI popped up and the pharmacist ended up telling him to not take his doxazosin on the nights that he takes his Levitra to avoid hypotension. They have two different MOAs but this interaction still was there, so now I guess I'm worried that I'll miss a similar interaction in the future. And getting a little confused about when simultaneous administration might lead to exacerbation of ADEs. For instance, if a patient is new on BOTH furosemide and a BB, is it being overly cautious/illogical to advise them to take them a few hours apart for the first couple of times until you know you're not experiencing too much dizziness from either? I know they have two different MOA but I just get worried...
 
No, I would tell them that it is okay to take both an ACE-I and a BB simultaneously. But for instance, the other day we had a patient who was taking Levitra and got a new script for doxazosin, and an DI popped up and the pharmacist ended up telling him to not take his doxazosin on the nights that he takes his Levitra to avoid hypotension. They have two different MOAs but this interaction still was there, so now I guess I'm worried that I'll miss a similar interaction in the future. And getting a little confused about when simultaneous administration might lead to exacerbation of ADEs. For instance, if a patient is new on BOTH furosemide and a BB, is it being overly cautious/illogical to advise them to take them a few hours apart for the first couple of times until you know you're not experiencing too much dizziness from either? I know they have two different MOA but I just get worried...

It's just dizziness, not QT prolongation. If people have multiple times that they take their meds, they are more likely to forget them. And just curious, are you on IPPEs or APPEs?
 
It's just dizziness, not QT prolongation. If people have multiple times that they take their meds, they are more likely to forget them. And just curious, are you on IPPEs or APPEs?

This. I'm telling people all the time that they should be taking their simvastatin at bedtime, but if they will be more compliant by taking it in the am, then stick with that.
 
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