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Help, how does decreasing AII cause renal failure?
Kluver_Bucy said:Help, how does decreasing AII cause renal failure?
omarsaleh66 said:On the flip side, if u are a diabetic and u are peeing out all this albumin, then u want to give ACEI so efferent arterioles are relaxed and u can decrease proteinuria. (I think this is right? I forgot??)
omarsaleh66 said:ATII maintains blood flow to the kidneys by its actions on the efferent arteriole. So if u have renal stenosis and u have problems getting blood to the kidneys in the first place, then renin is secreted and u get ATII, aldosterone to maintain adequate blood pressure to your kidneys. That's why ACE inhibitors are contraindicated in renal artery stenosis.
On the flip side, if u are a diabetic and u are peeing out all this albumin, then u want to give ACEI so efferent arterioles are relaxed and u can decrease proteinuria. (I think this is right? I forgot??)
Also, if u give ACEI to a pregnant woman, the fetal kidneys dont develop and u get oligohydramnios and Potters syndrome (this might show up on step 1? )
later