Like StartingOverVet, we have a couple of PhD's, several MS's, a lot of us with previous careers (though I don't really consider the folks who have been vet techs for two-three application cycles right after undergrad as non-trads) and it works. I have noticed a few more differences; fewer traditional students are as impacted by the life, health and well-being of spouses and children, and with needing to help their own parents with various concerns. I certainly don't drink or go sleep deprived as much as some of the younger students, and some of the big concerns they have aren't on my plate (no upcoming weddings, dating, engagements, etc.)
Realisticly though, everyone has their own priorities, and the only real issues I have had being a student is dealing with living 3.5 hours from my husband and our house....and now dealing with his lay off as the sole income in the family, having to help my parents/grandparents financially in the past, having an established household of 8 pets (vs when I came out of undergrad with a tortoise and a tarantula), needing to stop fostering (don't think many trad students are foster parents to humans), and the general family obligations that come with all that. I think there are some huge advantages; I relate really well to most of our instructors, I am comfortable in surgery and clinics, I don't get upset when clients are difficult, things that would have upset me when I was 21 aren't a big deal now, technology has improved massivly since I was in college and I love note taking on a laptop (couldn't have afforded one if I had gone the traditional route), and I have a solid network outside of school/vet med. I also have a business that I can continue to run while in school (not great money, but useful) and I have a background that earns speaking gigs that pay, which is a nice supplemental income.