rpatel8

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I am confused. I don't know if its from overstudying or what but here is my question.

So in biology, we are taught that catabolism releases energy and drives anabolism. For example, the hydrolysis of ATP releases energy and is exothermic. Anabolism requires energy to make more complex structures.

But this is where I am confused. In chem, we are taught that breaking bonds requires energy and is endothermic and making bonds releases energy and is exothermic. Am I getting something backwards here or can these concepts not be related like I am trying to do?
 
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It is a good question. I think it's because the types of bonds. The bonds of ATP contain so much energy because of the electrostatic repulsion. And itay take a little bit of energy to break but it releases more energy than required.
 
Jul 7, 2011
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I am confused. I don't know if its from overstudying or what but here is my question.

So in biology, we are taught that catabolism releases energy and drives anabolism. For example, the hydrolysis of ATP releases energy and is exothermic. Anabolism requires energy to make more complex structures.

But this is where I am confused. In chem, we are taught that breaking bonds requires energy and is endothermic and making bonds releases energy and is exothermic. Am I getting something backwards here or can these concepts not be related like I am trying to do?
I think you're getting the term exothermic and exergonic mixed. Hydrolysis of ATP is endothermic, but weakly.

edit: also, the form of energy released in an exothermic reaction is typically heat or light. In exergonic, it's energy in the form of work that's released.

edit edit: scanned the wiki page, cleavage of the phosphate bond is actually exothermic, too. It's exothermic because the HBonds formed between ADP and Pi is stronger than the cleaved bond. TIL
 
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radmazindds

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The ADP-P bond in ATP is exceptionally high in energy (aka very unstable) and breaking it is exothermic because that would stabilize the molecule.

On the other hand, breaking the bonds of glucose, for example, DOES require an initial input of energy, but the net result is a higher yield of energy (like an investment).

Not sure if that answered your question but that's how I'm seeing it.

I am confused. I don't know if its from overstudying or what but here is my question.

So in biology, we are taught that catabolism releases energy and drives anabolism. For example, the hydrolysis of ATP releases energy and is exothermic. Anabolism requires energy to make more complex structures.

But this is where I am confused. In chem, we are taught that breaking bonds requires energy and is endothermic and making bonds releases energy and is exothermic. Am I getting something backwards here or can these concepts not be related like I am trying to do?
 

rpatel8

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On Topscore 1, there was a question that asked about the hydrolysis of ATP. The answer choices included "drives cellular work" AND "is an exergonic process". Wouldn't both of those be valid answer choices?
 

radmazindds

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An exergonic process is one in which the products are more stable than the reactants.

Sounds right to me. What did they have as the correct answer?

On Topscore 1, there was a question that asked about the hydrolysis of ATP. The answer choices included "drives cellular work" AND "is an exergonic process". Wouldn't both of those be valid answer choices?
 
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I think you're generalizing bonding. Some are thermodynamically favorable because the proiducts result in a lower potential energy. Think about ATP formation, you have to force three negatively charged phosphates in close proximity. This is quite a bit of potential energy, and will need an "investment" of energy. This is accomplished by the coupling of the breakdown of a molecule that releases even more free energy than is required to form the ATP. In the case of oxidative phosphorylation, the potential energy built up from the electrochemical gradient of the ETC provides this source of free energy. The subsequent "fall" of the protons is coupled to the formation of ATP. Likewise, the hydrolysis of ATp provides the free energy to drive lesser endothermic processes.
 

crew09

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damn.

Checked 2 sources and they both say hydrolysis of ATP is EXERgonic.

Wiki

The description and typical textbook labeling of ATP phosphanhydridic bonds as "high energy bonds" can be very misleading to students. These bonds are in fact relatively weak. They do involve high energy electrons but the bonds themselves are quite easy to break.



As noted below, energy is released by the hydrolysis of ATP when these weak bonds are broken - requiring a small input of energy, followed by the formation of new bonds and the release of a larger amount of energy as the total energy of the system is lowered and becomes more stable.

hydrolysis of the phosphate groups in ATP is especially exergonic...
 

toothhornet88

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Yeah I looked for it everywhere and could not come to an answer. I think it's a good idea to email each other's chem or bio professors and see what they say! :D
I know it's summer and all but some professors actually do respond to emails during vacation
 
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Yeah I looked for it everywhere and could not come to an answer. I think it's a good idea to email each other's chem or bio professors and see what they say! :D
I know it's summer and all but some professors actually do respond to emails during vacation
according to wiki, the enthalpy change is exothermic.
 

crew09

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Found 2 older threads that talk about this exact question, both strongly suggest that hydrolysis of ATP is EXERgonic.

http://forums.studentdoctor.net/showthread.php?t=760207&highlight=
http://forums.studentdoctor.net/showthread.php?t=821501&highlight=

OP,

I looked at your original question, and I think your over-generalizing.

we are taught that breaking bonds requires energy and is endothermic
Exregonic rxns still require a small input of energy to overcome Energy of Activation. Simply requiring energy to perform a rxn doens't mean it's Endergonic.

I hope I didnt confuse you more.....
Anyone else feel free to add/correct.
 
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Jul 7, 2011
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Found 2 older threads that talk about this exact question, both strongly suggest that hydrolysis of ATP is EXERgonic.

http://forums.studentdoctor.net/showthread.php?t=760207&highlight=
http://forums.studentdoctor.net/showthread.php?t=821501&highlight=

OP,

I looked at your original question, and I think your over-generalizing.



Exothermic rxns still require a small input of energy to overcome Energy of Activation. Simply requiring energy to perform a rxn doens't mean it's endothermic.

I hope I didnt confuse you more.....
Anyone else feel free to add/correct.
it's both exothermic and exergonic.

http://en.wikipedia.org/wiki/Adenosine_triphosphate

5th paragraph under properties
 

crew09

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Thanks.

Makes sense, I think we were confusing change in free energy spontaneous/nonspontaenous (-gonic) vs. enthalpy (-thermic) absorption/release of thermal energy.

I think OP meant -gonic in his original question, either way doens't matter i'm sure he's gonna lay waste to the DAT and post a killer breakdown tomorrow :)
 
Jan 23, 2010
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In a single molecule:
To break a bond requires energy
To make a bond releases energy

Catabolism is a reaction with reactants and products.

In catabolism, old bonds are broken (which requires energy) and new bonds are made (which releases energy). When you balance out the net energy of this reaction/catabolic process, it is found that the required energy to break the bonds is LESS than the energy that was released when making the new bonds.

Macromolecule bond breaking_energy required < Micromolecule bond making_energy released

NET result: energy released

Essentially, the smaller molecules are more STABLE than the macromolecules.
Why? Because a release of energy puts you in a lower energy state making you more stable

Keep this thought process bolted in mind for all reactions (bio/orgo/chem)
 
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Jul 26, 2011
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Even though I like how you put together things to make sense, but it always troubled to make sense how in bio... ATP hydrolysis (breaks bond) is exergonic and releases energy and in GC... you release energy from making a bond in exothermic reaction.

My conclusion was just to treat them separately, don't try to link them you will just confuse yourself even more. Whatever was taught in bio, just try to make sense within bio topic itself and vice versa for other subjects.
 
Jul 7, 2011
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Even though I like how you put together things to make sense, but it always troubled to make sense how in bio... ATP hydrolysis (breaks bond) is exergonic and releases energy and in GC... you release energy from making a bond in exothermic reaction.

My conclusion was just to treat them separately, don't try to link them you will just confuse yourself even more. Whatever was taught in bio, just try to make sense within bio topic itself and vice versa for other subjects.
According to wiki, the HBonds between ADP and Pi are stronger than the cleaved ATP bond
 
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