causes of low oxygen sat: everything?

[Azipropofol]

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ok so following pathoma's logic that anything that interrupts the continuum of: fi02-->PA02-->Pa02-->Sa02 will lead to low o2 sat, I guess pretty much EVERY respiratory disturbance will cause low o2 sat? For example, I know anemia will not cause low sat but say holding your breath?

 

[Azipropofol]

no one wants to bite?