Cellular respiration- aerobic/ anaerobic

[Moshi123]

On Craig Savage's video on Cellular respiration, he said Glycolysis is anaerobic but I found on Wikipedia that Glycolysis in humans, aerobic conditions produce pyruvate and anaerobic conditions produce lactate.

Could anyone please clarify me on these questions?
-Is Glycolysis aerobic or anaerobic for cellular respiration?
-Are Kreb cycle and Electron transport chain aerobic?

Thank you!

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[chemkay]

Check out the cliffs AP bio notes of this section. They do a really nice job breaking it down, and they are FREE!

But glycolysis is an aerobic process used to break glucose into 2 pyruvates, which will enter krebs, and all the NADH/FADH2 will use the ETC, where final electron acceptor is 02, hence aerobic. Without 02, you would have lactic acid fermentation which would be taken back to the liver to make pyruvate (called the Cori Cycle). This is also the reason your muscles get sore after a workout, lactic acid buildup from the lack of O2. Hope that makes sense!

 

[7amsho]

glycolysis is anaerobic, you don't need oxygen for it to occur, all you need are ATP, glucose, and enzymes
once glycolysis is over, if there is any oxygen (aerobic), then pyruvate proceeds via the PDH then Krebs cycle
if there is no oxygen (anaerobic), it will go through fermentation and produce lactate (in humans) or ethanol and CO2 (in yeast)

krebs cycle and ETC are aerobic because if you didn't have any oxygen, pyruvate wouldn't have went through PDH then Krebs cycle, instead it would have went through fermentation

i hope this helps

 

[BigCountry]

Glycolysis is a facultative anaerobic process. It occurs in humans as well as bacteria and doesn't need oxygen to proceed. In bacteria glycolysis produces ethanol. In humans when no oxygen is present lactic acid is made. If O2 is present then the pyruvate is transferred from the cytosol into the mitochondrial matrix, undergoes pyruvate decarboxylation which means it is transformed into acetyl CoA then enters the Krebs cycle.

 

[chemkay]

^ this is correct. I am stuck in a math studying haze... Lol. It's anaerobic

 

[Moshi123]

Awesome! Thanks a lot for the explanations!

I have another questions..
On one of the Cliffs questions, it says Pyruvate produces 15 ATP, Acetyl CoA produces 12 ATP.

Could anyone please explain how pyruvate produces 15 ATP and Acetyl CoA produces 12 ATP?

Thanks!!

 

[tooth knockn]

Yea and while we are at it, how come the world spins ?

 

[tooth knockn]

Thanks ! ! !