Question about aerobic and anaerobic respiration

[deleted1189988]

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So, lets say if oxidative phosphorylation were to stop working due to the lack of oxygen, then that means an organism depending on what it is will do glycolysis, and then a type of fermentation. So if oxidative phosphorylation stops working, then can we still do pyruvate carboxylation and krebs cycle, no right. BOTH pyruvate decarboxylation and krebs cycle come to a stop eventually to indirectly!

 

[DAT Destroyer]

So, lets say if oxidative phosphorylation were to stop working due to the lack of oxygen, then that means an organism depending on what it is will do glycolysis, and then a type of fermentation. So if oxidative phosphorylation stops working, then can we still do pyruvate carboxylation and krebs cycle, no right. BOTH pyruvate decarboxylation and krebs cycle come to a stop eventually to indirectly!

If oxidative phosphorylation stops, other metabolic cycles like the citric acid cycle (also known as the Krebs cycle) will eventually slow down or halt due to a buildup of NADH and FADH2, which are the electron carriers needed to drive oxidative phosphorylation; without a way to "dump" these electrons, the reactions in the citric acid cycle that generate them cannot continue efficiently, leading to a disruption in the overall cellular energy production

Hope this helps
Dr. Jim Romano