- Joined
- Nov 6, 2006
- Messages
- 214
- Reaction score
- 3
Chicanery or Legit?
- Thread starter pretenda
- Start date
- Joined
- Apr 7, 2011
- Messages
- 5,313
- Reaction score
- 1,086
KA-CHING$
$ aside it's impossible to know without a study. Pain alone is too susceptible to placebo. Perhaps bonescan before/after tx's? If he uses it for inflammatory arthridities then CRP/ESR pre-post tx.
Sounds like prp... All studies to date for oa and prp are neg or inconclusive
froma physiologic standpoint, it makes no sense. sorta like our boy rick perry and his stem cell back treatments
"I am the only one to have found a way to cure arthritis," he said.
give me a effing break......
"I am the only one to have found a way to cure arthritis," he said.
give me a effing break......
Last edited:
- Joined
- May 8, 2004
- Messages
- 4,159
- Reaction score
- 1,860
http://www.wehling-hartmann.de/
see youtube video at bottom
notice injection taking place without the aid of any type of imaging modality at 1:12.
see youtube video at bottom
notice injection taking place without the aid of any type of imaging modality at 1:12.
- Joined
- May 30, 2005
- Messages
- 23,118
- Reaction score
- 14,672
Because he is German, it must be better.
I love the mask and gloves, but done on an exam room table with a 3.5" needle and no fluoro. Total bunk.
It's just PRP.
What about the Pain Doc for the news guy from NY. Because of the MRI with small hairline fractures and a disk bulge, you cannot play golf again. Idiot.
SML
I love the mask and gloves, but done on an exam room table with a 3.5" needle and no fluoro. Total bunk.
It's just PRP.
What about the Pain Doc for the news guy from NY. Because of the MRI with small hairline fractures and a disk bulge, you cannot play golf again. Idiot.
SML
- Joined
- Nov 6, 2006
- Messages
- 214
- Reaction score
- 3
Kinda seems unprofessional to do a piece about some treatment and then keep blathering on about your own problem...
It looks like prp to he inter spinal ligament?!?! Wtf. Why not prolo, what's the difference. Silly.
Also that guys "slipped disc" has bothered him for 11 years?
- Joined
- Jan 9, 2002
- Messages
- 6,526
- Reaction score
- 3,103
Image guided PRP and prolo work QUITE well in issues with soft tissue injury.
- Joined
- Feb 25, 2010
- Messages
- 4,263
- Reaction score
- 1,560
Very suspect, in my opinion.
- Joined
- May 30, 2005
- Messages
- 23,118
- Reaction score
- 14,672
You want to write the protocol for intradiscal PRP?
Discs are soft tissue.
Just need PRP and lime jello. Mmm, jello.
J Orthop Res. 2011 Feb;29(2):265-9. doi: 10.1002/jor.21210.
Interleukin-1β induces angiogenesis and innervation in human intervertebral disc degeneration.
Lee JM, Song JY, Baek M, Jung HY, Kang H, Han IB, Kwon YD, Shin DE.
Source
Department of Orthopaedic Surgery, CHA Bundang Medical Center, CHA University, Gyeonggi-do 463-712, Korea.
Abstract
Degenerative disorders of the intervertebral discs (IVDs) are generally characterized by enhanced matrix degradation, angiogenesis, innervation, and increased expression of catabolic cytokines. In this study, we investigated the effects of inflammatory cytokines, IL-1β, and TNF-α, on the expression of an angiogenic factor, vascular endothelial growth factor (VEGF), and neurotrophic factors, nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), in human IVD degeneration. IL-1β and TNF-α stimulated the gene expression of VEGF, NGF, and BDNF in nucleus pulposus (NP) cells isolated from patient tissues. Immunohistochemical results demonstrated a positive correlation between IL-1β and VEGF/NGF/BDNF expression in human IVD tissues. RNA expression analysis of patient tissues also identified positive correlations between VEGF and platelet endothelial cell adhesion molecule-1 (PECAM-1) and between NGF/BDNF and protein gene product 9.5 (PGP9.5). Our findings suggest that IL-1β is generated during IVD degeneration, which stimulates the expression of VEGF, NGF, and BDNF, resulting in angiogenesis and innervation.
Tissue Eng Part A. 2009 Dec;15(12):3719-27.
Characterization of in vivo effects of platelet-rich plasma and biodegradable gelatin hydrogel microspheres on degenerated intervertebral discs.
Sawamura K, Ikeda T, Nagae M, Okamoto S, Mikami Y, Hase H, Ikoma K, Yamada T, Sakamoto H, Matsuda K, Tabata Y, Kawata M, Kubo T.
Source
Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan. [email protected]
Abstract
We have previously shown that administration of platelet-rich plasma-impregnated gelatin hydrogel microspheres (PRP-GHMs) into a degenerated intervertebral disc (IVD) markedly suppresses progression of IVD degeneration. In the current study, we characterized the in vivo effects of PRP-GHM treatment in a degenerated IVD model in rabbit. On magnetic resonance images, the IVD height was significantly greater after treatment with PRP-GHMs compared with phosphate-buffered saline-impregnated GHMs, PRP without GHMs, and needle puncture only. Water content was also preserved in PRP-GHM-treated IVDs. Consistent with this observation, the mRNA expression of proteoglycan core protein and type II collagen was significantly higher after PRP-GHM treatment compared with other treatment groups. No proliferating cells were found in the nucleus pulposus and inner annulus fibrosus in any groups, but the number of apoptotic cells in the nucleus pulposus after PRP-GHM treatment was significantly lower than that after other treatments. These results provide an improved understanding of the therapeutic effects of PRP-GHM treatment of degenerated IVDs.
