That's pretty freaking tricky. According to my notes from the GINA Expert Panel 3, the equivalent medium daily doses of budesonide and fluticasone are around 400-800mcg and 250-500mcg/day, giving us roughly a 40:25 (or 8:5) budesonide:fluticasone ratio.
As to formoterol and salmeterol, my notes say that 12mcg of formoterol is equivalent to 50mcg of salmeterol (a 12:50 ratio). Both of these are generally dosed BID (up to 24 mcg qd for formoterol and up to 100mcg qd of salmeterol).
The problem lies in the formulation of the inhalers. Symbicort comes in two strengths: 80/4.5 and 160/4.5. The Advair Diskus comes in three strengths (colors): 100/50, 250/50 and 500/50 (the HFA comes as 45/21, 115/21, and 230/21.) There just isn't a mathematical way to get ~400/12 dose of symbicort equal to a 250/50 dose of advair. The closest way to get equivalent doses would be 2 puffs BID of the 160/4.5 Symbicort to 1 puff BID Advair (I know that this is actually "considered" to be equivalent, but it isn't exactly).
Soooo... even though I may be off the mark for Epic's question, I'll pose one of my own (probably pretty easy): What, if any, drug therapy alternatives are there to hydralazine for preeclampsia or gestational hypertension?
