competitive inhibition question

[kfcman289]

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My EK book said that increasing substrate concentration would increase the rate after something has undergone competitive inhibition. Would increasing temperature or increasing the pH do anything as well?

 

[workethic712]

perhaps there would be indirect effects from changing those factors but the most important, need-to-know fact about competitive inhibition is that it can be overcome by increasing substrate concentration.

 

[jcb123]

workethic is right talking about the pH and temp is not really relating with inhibition of an enzyme

Increasing temp or pH would probably degrade your enzyme or alter the reactivity of the active site.....

 

[dyspareunia]

My EK book said that increasing substrate concentration would increase the rate after something has undergone competitive inhibition. Would increasing temperature or increasing the pH do anything as well?

Changing temp or pH can affect the enzyme's activity, but by definition a competitive inhibitor binds to the active site just like the normal substrate does so there would be no net difference in terms of inhibition.