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- Feb 24, 2013
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Quick question:
I know with benzylic electrophiles, sometimes E2 creates a hoffman product over even a tertiary subtituted zaitsev product because it creates a conjugated system.
Is this the same for a simple allylic electrophile as well? It creates a conjugated system but not to the extent of a benzylic electrophile.
Simplified question:
Benzylic hydrogen>tertiary hydrogen for E2
However, does Allylic hydrogen>tertiary hydrogen for E2?
Will an allylic hydrogen also favor a hoffman product?
I know with benzylic electrophiles, sometimes E2 creates a hoffman product over even a tertiary subtituted zaitsev product because it creates a conjugated system.
Is this the same for a simple allylic electrophile as well? It creates a conjugated system but not to the extent of a benzylic electrophile.
Simplified question:
Benzylic hydrogen>tertiary hydrogen for E2
However, does Allylic hydrogen>tertiary hydrogen for E2?
Will an allylic hydrogen also favor a hoffman product?