I tried looking in previous threads but the answer was never really given....
FA says there is increased urine urobilinogen in Gilbert and Crigler....but this makes no sense to me. To get increase urine urobilinogen, you have to have direct bilirubin be made in liver first to be excreted into the gut.
GILBERT = poor uptake and poor conjugation, hence LOW direct bilirubin being made
CRIGLER = poor conjugation, hence LOW direct bilirubin being made
So....why does FA say it increases urine urobilinogen?
FA says there is increased urine urobilinogen in Gilbert and Crigler....but this makes no sense to me. To get increase urine urobilinogen, you have to have direct bilirubin be made in liver first to be excreted into the gut.
GILBERT = poor uptake and poor conjugation, hence LOW direct bilirubin being made
CRIGLER = poor conjugation, hence LOW direct bilirubin being made
So....why does FA say it increases urine urobilinogen?