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I'd go with the chemo alone here. I believe Neo-Aegis demonstrated slightly better outcomes with chemorads frankly, but any benefit has to be weighed against toxicity. Perioperative chemo reasonable in the non-irradiated patient and preferable here.Well that took all of a week. One of our satellite providers called me for help. They have a patient with a large lower esophageal adeno in a patient they treated for a different thoracic malignancy a few years ago asking me what options they have. The surgeon wants preop CRT but they are worried about how to deal with the prior dose. Hmm