Step I cryptorchidism

Started by hopeinternist
Get help with your application

Use all the free resources available to you from SDN: articles, guides, expert advising, forums discussions, and school research.

Browse articles Compare schools My application plan Read Interview Feedback
Practice for interviews Ask an Advisor
H

hopeinternist

New Member
15+ Year Member
FA2013 pg 536- says that LH increases and testosterone can be low or normal based on whether its one nut or both nuts descended.. but also says Leydig cells are unaffected by temperature. Any idea why LH increases, if leydig are not affected? UW says LH and testosterone are normal because leydig cells are not affected by the condition. Does LH go up just because FSH went up due to lack of inhibin from dysfunctional Sertoli Cells? Thanks QId 582
 
Sort by date Sort by votes
hopeinternist said:
Does LH go up just because FSH went up due to lack of inhibin from dysfunctional Sertoli Cells? Thanks QId 582
Click to expand...

Inhibin technically shouldn't affect LH, as it affect the anterior pituitary directly to decrease FSH (not through decreased GnRH). So when inhibin decreases, it shouldn't have an effect on LH, according to FA/BRS.

However this article (http://www.ncbi.nlm.nih.gov/pubmed/11423739) says in bilateral, FSH and LH will both be high, and so does FA.

So to answer your question, 😕😕😕
 
Upvote 0 Downvote
You must log in or register to reply here.