Cushing Response

[velvethead]

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Anyone know why the respiratory rate slows in the Cushing response??? I understand why the blood pressure rises and why the heart rate slows.

I would think that with cerebral ischemia, the central chemoreceptors would stimulate breathing, not suppress it.

 

[velvethead]

Anyone know why the respiratory rate slows in the Cushing response??? I understand why the blood pressure rises and why the heart rate slows.

I would think that with cerebral ischemia, the central chemoreceptors would stimulate breathing, not suppress it.

*bump*

 

[yaah]

Anyone know why the respiratory rate slows in the Cushing response??? I understand why the blood pressure rises and why the heart rate slows.

I would think that with cerebral ischemia, the central chemoreceptors would stimulate breathing, not suppress it.

Central chemoreceptors aren't the only thing at play. Increased intracranial pressure causes pressure on areas that regulate respiratory and cardiac rate (reticular activating system). The findings are not always respiratory depression. The key is respiratory irregularity - which can be altered pattern or rate. It sort of depends on where in the brainstem the damage is felt the most.

See here http://hsc.unm.edu/touch/datasets/datasets/definitions/cushing.htm

 

[i61164]

Anyone know why the respiratory rate slows in the Cushing response??? I understand why the blood pressure rises and why the heart rate slows.

I would think that with cerebral ischemia, the central chemoreceptors would stimulate breathing, not suppress it.

Respiratory irregularity is from impaired brainstem function (Blumenfeld pg. 139).

 

[velvethead]

Central chemoreceptors aren't the only thing at play. Increased intracranial pressure causes pressure on areas that regulate respiratory and cardiac rate (reticular activating system). The findings are not always respiratory depression. The key is respiratory irregularity - which can be altered pattern or rate. It sort of depends on where in the brainstem the damage is felt the most.

See here http://hsc.unm.edu/touch/datasets/datasets/definitions/cushing.htm

That website was EXACTLY the kind of explanation I was looking for yesterday, yet somehow Google couldn't help a guy out....

Thanks.