cushings syndrome and proximal muscle weakness

[cheruka]

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Does anyone know why cushing's can cause proximal muscle weakness?
Thanks!

 

[Transposony]

Does anyone know why cushing's can cause proximal muscle weakness?
Thanks!

By causing Hypokalemia

 

[gravitywave]

By causing Hypokalemia

less this and more because cushings -> lots of cortisol -> protein catabolism -> proximal myopathy.

 

[MrBeauregard]

I thought excessive exogenous steroids/hypercortisolism also led to selective Type II fiber atrophy? Maybe that's a contributing factor.