Step I Cystic fibrosis

[DrPak]

Advertisement - Members don't see this ad

A usmlerx question asked which transport channel is defective in Cystic fibrosis. It had both Na+ and Cl- listed as options. I thought BOTH were defective, but as it turns out, it seems to be only Cl-. Is this right, because my Goljan Rapid Review says it's a Na+ and Cl- channel problem?

 

[Buckeye(OH)]

Its the CFTR - so it is the Cl- and not the Na+

 

[G0S2]

A usmlerx question asked which transport channel is defective in Cystic fibrosis. It had both Na+ and Cl- listed as options. I thought BOTH were defective, but as it turns out, it seems to be only Cl-. Is this right, because my Goljan Rapid Review says it's a Na+ and Cl- channel problem?

CFTR affect chloride transport directly. This will indirectly affect Na homeostasis.