destroyer ochem 4

[topdent1]

I don't understand destroyers explanation of why the Nitrogen farthest away attacks the carbonyl. My exam is in 21 hours. HELP!

 

[doc3232]

Was it 6 carbons away?
I don't have destroyer but I do want to help.

 

[TeamGuo]

this is just immine mechanism.

Reacting aldehyde with primary amine. the N farthest away in this case is most basic, it's farther away from the carbonyl.

 

[topdent1]

Got it. I didn't realize that this molecule was an amide and the nitrogen farthest away is most basic, thus most likely to give up electrons. SIlly me. 👍