Difference between dromotropic vs. chronotropic?

This forum made possible through the generous support of SDN members, donors, and sponsors. Thank you.

beatsbydre

Full Member
10+ Year Member
Joined
Apr 11, 2012
Messages
110
Reaction score
0
Dromotropic and chronotropic both relies on SA/AV nodal action potential (Phase 0,3,4). I'm wondering why chronotropic relies on inward Na+ current during Phase 4, and why dromotropic relies on inward Ca++ current during Phase 0. I think they all do the same thing?

Can someone explain it to me like I'm five?

Members don't see this ad.
 
I couldn't tell you why one channel is preferred in one node versus the other, but chronotropic effects come mainly from the SA node and dromotropic from the AV node. The chrono- effect is about a rate of firing, so it's more relevant to think of the SA node as it's in control of the basal firing rate. The dromo- effect is more of a speed/conduction effect, so it's best to think of that at its rate-limiting location, the AV node (the place in the heart with the slowest conduction).
 
Top