ChessMaster3000

7+ Year Member
Mar 7, 2010
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I've never understood the difference btw the two. FA said HSP is a vasculitis secondary to IgA complex deposition and that it is associated with IgA nephropathy. Sounds like HSP is really just an IgA nephropathy, not just assoicated with it. If not, what IS IgA Nephropathy and how is it different?
 

Trogghunter

7+ Year Member
Nov 16, 2009
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Attending Physician
I am over a year past taking step 1, but we had this come up in real life last week. Our patient had likely HSP....more systemic side effects like GI discomfort, a rash on the buttocks and hamstrings. I think that the differentiation is in the clinical presentation and the timing of the disease.
 
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ChessMaster3000

7+ Year Member
Mar 7, 2010
739
217
Status
I am over a year past taking step 1, but we had this come up in real life last week. Our patient had likely HSP....more systemic side effects like GI discomfort, a rash on the buttocks and hamstrings. I think that the differentiation is in the clinical presentation and the timing of the disease.

cool. would you say HSP is IgA nephropathy PLUS some systemic symptoms such as GI/derm? Im trying to figure out if FA really meant to say "associated with" as opposed to something else
 

ninjasurgeron

5+ Year Member
Jul 16, 2012
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Medical Student
HSP is the one with extrarenal manifestations. I think the age range differs between the two diseases too.
 
Jun 11, 2012
341
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Medical Student
I've never understood the difference btw the two. FA said HSP is a vasculitis secondary to IgA complex deposition and that it is associated with IgA nephropathy. Sounds like HSP is really just an IgA nephropathy, not just assoicated with it. If not, what IS IgA Nephropathy and how is it different?
I'm all for explaining but questions like these are for google, no?