I think they're pretty distinct, but there's a lot of overlap in information. Pathophys can be thought of as clinical pathology - lab values, symptoms, basic mechanisms of disease. Pathology is more the study of the tissues themselves and how they change in disease state. I think of pathology as more related to the science of disease than the clinical aspects of disease. So for example, in diabetes, pathology would explain how the pancreas changes, genetic links, what you can expect to see on histological examination, risk factors, symptoms, etc. Pathophys would help you understand what you might see on a chem 7 (Na, K, Cl, bicarb, BUN, creatinine, and glucose), how these values will fluctuate post-treatment, systemic effects (in this case, renal and pulmonary) that you might expect to see, etc.