Many of them take it along with their opioids to enhance the effect - when I worked at the methadone clinic, lots of the clients took a minimum of 100 mg dimenhydrinate with their meth. One client took at least four or five of the 50 mg tablets, washing them down with 100 mg methadone in Tang. Another two clients, brothers, bought 2 bottles of 100 tablets weekly when they picked up their methadone carries.