Disulfide linkage belongs to secondary or tertiary?

[libraryismyhome]

EK said that S-S belongs to tertiary while BR said that S-S belongs to secondary but more common in tertiary.

What should I answer for MCAT? I vaguely remember that tertiary was the right answer for AAMC, but I am dubious about this.

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[dsoz]

I vote tertiary. Secondary is alpha helix or beta pleated sheets. Tertiary is the folding and interactions between sections of the sequence.

Dsoz

 

[GreenRabbit]

Tertiary.

Secondary structure does not involve disulfide bonds. Alpha helixes / beta sheets contain hydrogen bonds.

 

[golgiapparatus88]

Tertiary.

Secondary structure does not involve disulfide bonds. Alpha helixes / beta sheets contain hydrogen bonds.

Agreed. But also just remember (if they want to be tricky) that disulfide bonds are DETERMINED by the peptides primary structure, not tertiary.