Round, definitely, if the numbers are close to easy numbers. 7.09 to 7, for example. But when it's not intuitive to round, I usually multiple both top and bottom by the same number to get rid of the decimals. For example, 7.25/11.75. Multiply both numbers by 4, and you get 29/47. Round to 30/50 and presto.
I typically avoid dividing by decimals so this is my go to. Scientific notation also makes big or small, or largely disproportionate, numbers easy to work with.
Hope this helps!