Their game has essentially been re-combining the same old chemotherapies. Almost every cancer still gets platinum, it seems.
After I signed up for ASCO membership, I started getting the med onc throwaway journals. I do often read them. I realized that there are a lot of targeted agents out there currently and in development. Most of them provide a progression free survival benefit only. Some do extend overall survival, though last year when I had a nice drug rep lunch (Chipotle!), the drug rep was telling me that only 4 targeted agents have ever extended survival greater than 4 months in solid malignancies due to the targeted agent alone.
These were: trastuzumab, ipilimumab, sipuleucel-T... I'm not sure what the fourth was. Let's say it's sunitinib. Costs: $70,000, $120,000, $93,000, $60,000/year.
The reality is that the studies you hear promoted in the throw away journals and in academic centers right now are all drug company funded because the agents are extremely expensive. Most are for the metastatic setting--read: maintenance chemo. Keep people on it a long time to increase profits. Many med oncs are on the edge of their seats to deliver these new targeted agents since they get a percentage of every bag they infuse (
http://ascoaction.asco.org/Home/tab...nistered-Drugs-The-Evolution-of-Buy-Bill.aspx). Researchers are promoting these drugs heavily to get funding from the drug companies to keep their research time.
We don't have much similar in rad onc. The funding from the device manufacturers is very limited. We don't have some technique we can come up with in a lab to all of a sudden make millions. The closest we have and the latest fad is to combine these targeted drugs with radiation. At least some trial money comes in that way.
So the grass may look greener on the other side, but for research, like everything else, it's all about the green. As long as the government is not giving grant money for research, options are going to be very limited for residents and attendings alike. I don't like the idea of selling my soul to push minimally more effective, extremely expensive medications to make someone else rich.