WiseOne Full Member 10+ Year Member Joined Jun 6, 2011 Messages 136 Reaction score 94 Apr 3, 2015 #1 Members do not see this ad. Does the release of intracellular materials into the extracellular space lead to autoimmune attack against those intracellular antigens?
Members do not see this ad. Does the release of intracellular materials into the extracellular space lead to autoimmune attack against those intracellular antigens?
S seminoma Full Member 7+ Year Member Joined Aug 9, 2014 Messages 1,976 Reaction score 1,030 Apr 3, 2015 #2 Yes if the necrosis occurs in previously immunologically isolated places. Wiki epitope spreading. This is a proposed mechanism of type 1 DM. Upvote 0 Downvote
Yes if the necrosis occurs in previously immunologically isolated places. Wiki epitope spreading. This is a proposed mechanism of type 1 DM.
A aspiringmd1015 Full Member 7+ Year Member Joined Mar 5, 2014 Messages 1,098 Reaction score 102 Apr 4, 2015 #3 also bc come compounds that are in the cell have never been exposed to the immune system, once they leak out of the cell they do get exposed, and thus AI reactions against them, and other compounds like them. Upvote 0 Downvote
also bc come compounds that are in the cell have never been exposed to the immune system, once they leak out of the cell they do get exposed, and thus AI reactions against them, and other compounds like them.
S solitarius Full Member 15+ Year Member Joined May 20, 2010 Messages 1,472 Reaction score 1,175 Apr 4, 2015 #4 Some times, but not always. Upvote 0 Downvote
Jabbed Full Member 10+ Year Member Joined Jan 30, 2013 Messages 1,928 Reaction score 2,435 Apr 4, 2015 #5 Jeopardy contestant: "I'll take 'Autoimmune Diseases' for $1,000." Alex Trebek: "The release of intracellular materials into the extracellular space leads to autoimmune attack against intracellular antigens." Jeopardy contestant: "What is SLE?" *thunderous applause* Upvote 0 Downvote
Jeopardy contestant: "I'll take 'Autoimmune Diseases' for $1,000." Alex Trebek: "The release of intracellular materials into the extracellular space leads to autoimmune attack against intracellular antigens." Jeopardy contestant: "What is SLE?" *thunderous applause*