Does the genetic problems on the DAT get any harder than this qvault question?

[panmit]

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Bicoid is an example of a maternal effect inheritance gene in D. melanogaster. Which of the following situations is absolutely necessary for the lethal expression of the bicoid phenotype?

A:
The father of the fly is homozygous for the mutant gene.

B:
The mother of the fly is homozygous for the mutant gene.

C:
The fly is homozygous for the mutant gene.

D:
The mother and father are heterozygous for the mutant gene.

E:
The fly is heterozygous for the mutant gene.



The answer is B and I get the answer, but there is no way I would have picked this answer if I didn't go over maternal effect inheritance in my undergrad class. How specific do we have to know about genetics? For example, AP Barron's has a list of all the autosomal/sex-linked diseases chart and there is no chance that I'm going to even try to memorize those.

All I am saying is after seeing this question, I am now very worried about the specific details on the Bio section.

 

[ICUrunning]

Bicoid is an example of a maternal effect inheritance gene in D. melanogaster. Which of the following situations is absolutely necessary for the lethal expression of the bicoid phenotype?

A:
The father of the fly is homozygous for the mutant gene.

B:
The mother of the fly is homozygous for the mutant gene.

C:
The fly is homozygous for the mutant gene.

D:
The mother and father are heterozygous for the mutant gene.

E:
The fly is heterozygous for the mutant gene.



The answer is B and I get the answer, but there is no way I would have picked this answer if I didn't go over maternal effect inheritance in my undergrad class. How specific do we have to know about genetics? For example, AP Barron's has a list of all the autosomal/sex-linked diseases chart and there is no chance that I'm going to even try to memorize those.

All I am saying is after seeing this question, I am now very worried about the specific details on the Bio section.

When you say AP barrons has a list, do you mean a list of disorders and whether or not they are autosomal or sex linked? ie. hemophilia, color blindness

Im in the same boat as you, I think it would be conducive to look at the pedigree picture.

 

[panmit]

Yeah, a list of around 10+ disorders. Some of them are not that bad because I have had exposure in my undergrad classes.

 

[mardr2b]

Can you post a list of the disorders ? maybe a picture
Thank you

 

[panmit]

Yeah sure,

Just remember breadth over depth. I think memorizing this list might be be too detailed.

But here ya go:

 

[ziggy1104]

I could be way off base here, but wouldn't you only have needed to see that the gene is uppercase D, therefore dominant. So, if the mom is homozygous dominant, she can only pass on that gene to her offspring (since she doesn't have the recessive gene). Therefore, whether the father has the gene or not, the offspring will get it regardless. I don't think we need to know detailed lists of disorders. Could be wrong, though! But I really hope I'm right!

 

[panmit]

I could be way off base here, but wouldn't you only have needed to see that the gene is uppercase D, therefore dominant. So, if the mom is homozygous dominant, she can only pass on that gene to her offspring (since she doesn't have the recessive gene). Therefore, whether the father has the gene or not, the offspring will get it regardless. I don't think we need to know detailed lists of disorders. Could be wrong, though! But I really hope I'm right!

Hey ziggy, where are you getting "uppercase D" from? D. melanogaster...because I think that is referring to the organism name.

To solve this problem, you need to know that maternal effect inheritance basically transfers all of the mothers genome to the offspring regardless of the genotype of the offspring.

You can read more about it here:

http://en.wikipedia.org/wiki/Maternal_effect

Also, you may be wondering that if the mother is homozygous mother possesses the lethal recessive trait, shouldn't she be dead? That's what I initially thought, but she could be alive if the mother's mother was heterozygous for the the recessive allele and passed it onto the mother. Basically, the mother possesses the lethal trait, but ultimately is only lethal to her offspring.

 

[Daneosaurus]

Hey ziggy, where are you getting "uppercase D" from? D. melanogaster...because I think that is referring to the organism name.

To solve this problem, you need to know that maternal effect inheritance basically transfers all of the mothers genome to the offspring regardless of the genotype of the offspring.

You can read more about it here:

http://en.wikipedia.org/wiki/Maternal_effect

Also, you may be wondering that if the mother is homozygous mother possesses the lethal recessive trait, shouldn't she be dead? That's what I initially thought, but she could be alive if the mother's mother was heterozygous for the the recessive allele and passed it onto the mother. Basically, the mother possesses the lethal trait, but ultimately is only lethal to her offspring.

Weird. We haven't gotten this far in my genetics class (6 week summer course, 1 week down, test on Wednesday). I'll be interested in this topic.

 

[ziggy1104]

Hey ziggy, where are you getting "uppercase D" from? D. melanogaster...because I think that is referring to the organism name.

To solve this problem, you need to know that maternal effect inheritance basically transfers all of the mothers genome to the offspring regardless of the genotype of the offspring.

You can read more about it here:

http://en.wikipedia.org/wiki/Maternal_effect

Also, you may be wondering that if the mother is homozygous mother possesses the lethal recessive trait, shouldn't she be dead? That's what I initially thought, but she could be alive if the mother's mother was heterozygous for the the recessive allele and passed it onto the mother. Basically, the mother possesses the lethal trait, but ultimately is only lethal to her offspring.

Holy crap, I was waaaay off! Wow, I hope the DAT doesn't get this deep into genetics. I've never even touched this material (haven't taken upper levels, though). Anyone who has taken the DAT have thoughts on whether we should know this stuff?

 

[panmit]

By the way, I got this question for DAT qvault. After searching around on SDN, they say qvault is on par, maybe a bit harder than the real DAT.