Elevated basophil levels means?

[dinesh]

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Google gave me
* viral infections
* urticaria
* post-splenectomy
* myxoedema
* ulcerative colitis
* systemic mastocytosis
* malignancy
* myeloproliferative disorders:
o chronic myeloid leukaemia
o myelofibrosis
o polycythaemia rubra vera
* haemolysis

The CBC of the person, showed Normal PNM, eosinophils etc, but elevated basophiles(.6 X 10^9) which is alot higher than normal.
What could be a good explaination for this?
The patient is a regular blood donor btw.
this is hypthetical 🙂 not a real patient!

 

[Rendar5]

cancer? cause i have absolutely no clue what they do (and neither does anyone as far as I know)

 

[dinesh]

....
Err...

 

[DrThom]

Allergic response not associated to parasitic infection?

 

[chris03333]

Google gave me
* viral infections
* urticaria
* post-splenectomy
* myxoedema
* ulcerative colitis
* systemic mastocytosis
* malignancy
* myeloproliferative disorders:
o chronic myeloid leukaemia
o myelofibrosis
o polycythaemia rubra vera
* haemolysis

isn't there something more reliable too look it up in (like a clin path book)? I am seriously asking this not to be mean (I am a vet student and would use veterinary clin path...) 😳

 

[orientedtoself]

From Henry: Clinical Diagnosis and Management by Laboratory Methods

"Basophilia is seen most frequently in allergic reactions, chronic myeloid leukemia, myeloid metaplasia (extramedullary myelopoiesis), and polycythmia vera. Relative basophilia may be transient following irradiation. Basophilia may be present in hypothyroidism and chronic hemolytic anemia and following splenectomy."

 

[GuP]

clinically, basophilia is usually associated with CML and PCV...im sure there are other causes but im sure in those instances there are other variables that tend to be more alarming....

 

[PiccoloPlaya]

You've got leukemia Better go see an oncologist/hematologist 😱

 

[Antiviral22]

The basophilia could be associated with a type I hypersensitivity reaction - a little more clinical history would be helpful.