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Elevated basophil levels means?

Discussion in 'Medical Students - MD' started by dinesh, Nov 21, 2005.

  1. dinesh

    dinesh Senior Member
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    Status:
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    Google gave me
    * viral infections
    * urticaria
    * post-splenectomy
    * myxoedema
    * ulcerative colitis
    * systemic mastocytosis
    * malignancy
    * myeloproliferative disorders:
    o chronic myeloid leukaemia
    o myelofibrosis
    o polycythaemia rubra vera
    * haemolysis

    The CBC of the person, showed Normal PNM, eosinophils etc, but elevated basophiles(.6 X 10^9) which is alot higher than normal.
    What could be a good explaination for this?
    The patient is a regular blood donor btw.
    this is hypthetical :) not a real patient!
     
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  3. Rendar5

    10+ Year Member

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    cancer? cause i have absolutely no clue what they do (and neither does anyone as far as I know)
     
  4. dinesh

    dinesh Senior Member
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    ....
    Err...
     
  5. DrThom

    DrThom Thundercat
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    Allergic response not associated to parasitic infection?
     
  6. chris03333

    chris03333 Veterinarian
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    isn't there something more reliable too look it up in (like a clin path book)? I am seriously asking this not to be mean (I am a vet student and would use veterinary clin path...) :oops:
     
  7. orientedtoself

    orientedtoself resident
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    From Henry: Clinical Diagnosis and Management by Laboratory Methods

    "Basophilia is seen most frequently in allergic reactions, chronic myeloid leukemia, myeloid metaplasia (extramedullary myelopoiesis), and polycythmia vera. Relative basophilia may be transient following irradiation. Basophilia may be present in hypothyroidism and chronic hemolytic anemia and following splenectomy."
     
  8. GuP

    GuP Senior Member
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    clinically, basophilia is usually associated with CML and PCV...im sure there are other causes but im sure in those instances there are other variables that tend to be more alarming....
     
  9. PiccoloPlaya

    PiccoloPlaya Membership Revoked
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    You've got leukemia :smuggrin: Better go see an oncologist/hematologist :eek:
     
  10. Antiviral22

    Antiviral22 Member
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    The basophilia could be associated with a type I hypersensitivity reaction - a little more clinical history would be helpful.
     

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