endochondral ossification

[hydroxyappatite]

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endochondral ossification is a procedure by which
1.hyaline cartillage is transformed into bone
2.calcified cartillage is replaced by bone
3.osteons with cartillage lamellae are formed
ans. is 2
should be 1. according to me ...?????

 

[DOCzee]

Cartilage never transforms into bone... it is replaced by bone in endochondral ossification. 1st a hyaline cartilage model is laid, then at the ossification zone the cartilage cells proliferate, hypertrophy and become dead. The dead cells are then calcified. The perichondrium,which by now has changed to periosteum, forms osteoblasts. These osteoblasts come in and lay the bone over the dead calcified cells. The dead cells degenerate later on.

I hope its clear now 🙂

 

[hydroxyappatite]

its very clear ..... thank u ........

 

[skabbaraju]

Cartilage never transforms into bone... it is replaced by bone in endochondral ossification. 1st a hyaline cartilage model is laid, then at the ossification zone the cartilage cells proliferate, hypertrophy and become dead. The dead cells are then calcified. The perichondrium,which by now has changed to periosteum, forms osteoblasts. These osteoblasts come in and lay the bone over the dead calcified cells. The dead cells degenerate later on.

I hope its clear now 🙂

Thats correct! So, can you also tell us in, which stage does the bone grow in length.? Is it proliferation or hypertrophy and maturation.?