Epilepsy

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qw098

zyzzbrah
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Hey guys,

Prof asked us a question and I was kind of stumped... was wondering what you guys thought.

He asked us if he thinks it would be better for a patient to have a generalized epilepsy or a focal/partial epilepsy?

What are your guys' thoughts? 🙂
 
Hey guys,

Prof asked us a question and I was kind of stumped... was wondering what you guys thought.

He asked us if he thinks it would be better for a patient to have a generalized epilepsy or a focal/partial epilepsy?

What are your guys' thoughts? 🙂
Focal if it were me. Less likely chance of waking up with a broken nose or having everyone freak out.
 
Hey guys,

Prof asked us a question and I was kind of stumped... was wondering what you guys thought.

He asked us if he thinks it would be better for a patient to have a generalized epilepsy or a focal/partial epilepsy?

What are your guys' thoughts? 🙂
Trick question. Id say neither. They both would suck honestly.
 
As Jibby said it would be best not to have any form of epilepsy. But the real answer to the Prof's question is that
it depends on the details. Most folks would assume that having a "focal" neurological problem is better than having
a "generalized" one, but it's not always the case, especially in epilepsy.

There are many forms of primary generalized epilepsy, such as Petit Mal, are genetically determined and have an extremely
good prognosis, meaning that they respond very well to medications. Others, such as Lennox-Gastaut, are dismal
diseases. Some focal onset epilepsies, like Rolandic Epilepsy, respond well to medication and resolve with age.

The fact is that most of the other focal onset epilepsies are due to focal brain injury from things like trauma,
infections, autoimmune disease, stroke, tumors, etc., that result in an epileptic focus of brain irritability. These
epileptogenic foci often spread and result in secondarily generalized (i.e. tonic-clonic) seizures. These focal-onset
secondarily generalized seizures are typically more difficult to control than idiopathic primary generalized (Petit Mal)
epilepsy.

Maybe this thread should be moved to the Neurology forum.
 
Good stuff guys, enjoyed the discussion.

Intuitively, I thought a focal type of lesion would be desired... as it should be with most cases. However, I learned that our professor tried to "trick" us by asking us this question. According to him, he prefers the general type of epilepsy for the same reason you mentioned neurodoc - the good prognosis (better response to medication).

Thanks guys for the responses - cheers!
 
Interestingly, surgery is sometimes more efficacious and may provide a better prognosis than medication. I.e. in mesial temporal lobe epilepsy, patients respond better to temporal lobectomies/amygdalohippocampectomies than to medication:

http://www.nejm.org/doi/full/10.1056/NEJM200108023450501

So like everything in medicine, 'it depends'
 
I agree Burgh, thanks for the paper. Interesting read!
 
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