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Step I FA 2013 error??
Started by Pinkleton
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On page 78 of FA 2013 it says that Ehlers Danlos syndrome is most frequently caused by defective type 1 or 5 collagen, whereas in FA 2012 it says type 3 (and the 2012 errata does not correct it). Could this be an error? I thought it was type 3
edit: please delete. someone posted about this already
yeah i noticed that too, googling told me that it's 1 and 3. i don't think there is a type 5 collagen, haha
yeah i noticed that too, googling told me that it's 1 and 3. i don't think there is a type 5 collagen, haha
It is type 5. It's in the errata for 2012 edition.
It is type 5. It's in the errata for 2012 edition.
wikipedia says I and III...and they don't even mention type V in the previous page, that's pretty weird.
wikipedia says I and III...and they don't even mention type V in the previous page, that's pretty weird.
http://en.wikipedia.org/wiki/Type-V_collagen
The page that you're talking about is talking about the different types of Ehlers-Danlos not different collagen types.
http://en.wikipedia.org/wiki/Type-V_collagen
The page that you're talking about is talking about the different types of Ehlers-Danlos not different collagen types.
oh wow that wording could have been better on that wikipedia page. anyways, thanks for the heads up.
since you asked.... the EDS subtypes are totally crazy. i had to memorize them for my boards, but for step 1 you should probably know type 1 is classic type and is col 5; type 4 is the vascular type and is col 3. Osteogenesis imperfecta and a very rare type of EDS are caused by col 1 mutations.
Ehlers-Danlos syndrome (EDS)
Type 1 (Gravis): AD, collagen 5.
Type 2 (Mitis): AD, collagen 5.
Type 3 (Benign hypermobile): AD, collagen 3.
Type 4 (Vascular): AD/AR, collagen 3:
Type 5 (X-linked): X-recessive. Lysyl oxidase deficiency.
Type 7 (Arthrochalasis multiplex congenita): AD/AR, COL1A/2,
Type 8 (Periodontitis): Type 3 collagen.
Type 9 (Occipital horn syndrome): XR Lysyl oxidase.
Type 10 (Fibronectin): AR, fibronectin.
Type 11 (Large joint hypermobile): AD: dislocation of large joints
Progeroid EDS: AR, xylosylprotein 4-beta-galactotransferase.
EDS with congenital adrenal hyperplasia: AR, tenascin-X
Ehlers-Danlos syndrome (EDS)
Type 1 (Gravis): AD, collagen 5.
Type 2 (Mitis): AD, collagen 5.
Type 3 (Benign hypermobile): AD, collagen 3.
Type 4 (Vascular): AD/AR, collagen 3:
Type 5 (X-linked): X-recessive. Lysyl oxidase deficiency.
Type 7 (Arthrochalasis multiplex congenita): AD/AR, COL1A/2,
Type 8 (Periodontitis): Type 3 collagen.
Type 9 (Occipital horn syndrome): XR Lysyl oxidase.
Type 10 (Fibronectin): AR, fibronectin.
Type 11 (Large joint hypermobile): AD: dislocation of large joints
Progeroid EDS: AR, xylosylprotein 4-beta-galactotransferase.
EDS with congenital adrenal hyperplasia: AR, tenascin-X
