FA pg 109

[super87]

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I have brain fog.

Under Homocystinuria, in the case of cystathione synthase deficiency, why does it say treatment includes increased B12 and folate in diet? It seems that those would pull the reaction backwards towards methionine and the problem here is that the pt is not making enough cysteine.

Halp.

 

[bobow98]

I think the reaction uses homoxystein to make methionine with b12 as the methyl mover. Increasing these two pathways will decrease your pool of available homocystein.

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