Factor V/Va and II/IIa?

[WashMe]

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If you need Xa, Va, calcium, and phospholipid to do II--->IIa (i.e., prothrombin to thrombin) and you need IIa to do V--->Va, how does this work? I suck at the coag stuff, but it seems that you need IIa to make Va but you need Va to make IIa, and I don't see where either one is made elsewhere. Thus, it's circuitous. The FA 2011 page is 345.

 

[nkhan]

Someone else posted this along time ago, hope it helps with the clotting stuff.

 

[WashMe]

Someone else posted this along time ago, hope it helps with the clotting stuff.

Thanks! You're awesome 🙂