Fall grades may or may not hurt or help you. I had not heard from Pittsburgh or New Jersey as of academic update period last year. I sent my updated grades (four A's - Genetics and three liberal arts classes; my school doesn't do A pluses, although it does do A minuses, stupid) and hoped the upward trend (all A's in that spring and summer, plus the new A's) would get me interviews. It didn't. I think if I had additionally retaken the DAT at that time and improved my score then, I may have gotten interviews ... but obviously my fall semester of A's made no difference at that time.