Fun With Chirality

[rah08e]

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I am comfortable with chirality but there is one nagging issue for me. Lets say you have a structure like this with 2 chiral centers but different attachments at the top and bottom when comparing both compounds:

View attachment photo.JPG


Would you assign "R" & "S" like normal, or do you have to fix one of the compounds so that each has the same attachments at the top and bottom. I hope what i'm asking is clear lol. Based on how I assigned R & S, these look like Diastereomers.

-Thanks!

 

[toothhornet88]

I am comfortable with chirality but there is one nagging issue for me. Lets say you have a structure like this with 2 chiral centers but different attachments at the top and bottom when comparing both compounds:

View attachment 17502


Would you assign "R" & "S" like normal, or do you have to fix one of the compounds so that each has the same attachments at the top and bottom. I hope what i'm asking is clear lol. Based on how I assigned R & S, these look like Diastereomers.

-Thanks!

Yes, that's right! Diastereomers

 

[rah08e]

Yes, that's right! Diastereomers

So it doesn't matter whats is attached to the top/bottom? Just assign R/S and ur good?

 

[toothhornet88]

So it doesn't matter whats is attached to the top/bottom? Just assign R/S and ur good?

Yeah, I wouldn't reconnect anything! Just leave it as it is and assign R/S