Generic depomedrol....any difference?

[smarterchild]

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Hi guys. I was looking to stock up my office with supplies and wanted to have some particulate steroids available for lumbar Esi, joints, etc. I have always used methylpred and wanted to stick with that. The prices are through the roof but using a generic equivalent of Depomedrol can save about 50%. A colleague told me not to get the generic. I was wondering what you guys thought and if you have experienced any differences between brand name and generic particulates? Thanks!

 

[Ducttape]

if it is from a reputable pharmaceutical company, then no difference.

if it is a compounded steroid... just look up recent history. google NECC steroid.

 

[smarterchild]

Thanks! the company is actually Teva. they even published the FDA's letter about its bioequivalency to Depomedrol. Thanks!

 

[Ferrismonk]

I think you'd be fine, agree with no compounded steroid.

Although, for what it's worth, I'd argue that using particulate in the epidural space might open you up to some liability.

 

[smarterchild]

Yes, you are correct. I am definitely using less and less of the particulates in the epidural space as I get older and wiser.

By looking at the labels, it seems that the only difference is the preservative. Depomedrol uses benzyl alcohol and the generic uses myristyl gamma picolinium chloride. Do you all have any experience between the 2 preservatives? are they both equally safe?

Thanks!

 

[clubdeac]

Yes, you are correct. I am definitely using less and less of the particulates in the epidural space as I get older and wiser.

By looking at the labels, it seems that the only difference is the preservative. Depomedrol uses benzyl alcohol and the generic uses myristyl gamma picolinium chloride. Do you all have any experience between the 2 preservatives? are they both equally safe?

Thanks!

Calling @algosdoc

 

[Aether2000]

Teva generic products contain identical ingredients to name brand. The final product is tested against name brand products and must be within a relatively small band of tolerance for ingredients (approx 5%). Generics are FDA approved and are considered safe. Avoid compounded products of any kind when possible and all the time for injectable steroids.

 

[smarterchild]

Thank you everyone! I appreciate all the good info!

 

[pastafan]

Difference that I have found is that the generic must be shaken a lot more to get everything in suspension. McKesson pricing not too much different between the two so I'm sticking to name brand for ease.

 

[smarterchild]

Oh really? McKesson is my supplier too and the price difference is almost double. This is with gpo pricing

 

[pastafan]

Oh really? McKesson is my supplier too and the price difference is almost double. This is with gpo pricing

What are you getting? With SIS GPO I'm paying $8.16 brand and $7.46 generic 40 mg single dose.