Oftentimes the particular agent used depends on which one is en vogue at that place and which one they have in the Pyxis. Ziprasidone does take longer to work than haloperidol or droperidol (which is fastest and probably the best). Multimodal sedation using benzos and antipsychotics is def better than using either alone. Regarding BZDs, a frequent mistake is to use Ativan rather than versed which is faster acting and has a shorter duration of action.