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None of them got approval for obesity until 2015 and it wasn't until the last 1-2 years that insurance would cover for that indication.
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GLP1 meds and fasting
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All fair points, although obesity is much more complex than many of us are aware of.
That being said, if we have a medication that makes people lose weight despite their bad habits it is still 100% worth it given how bad obesity is for people and how expensive it is to treat the complications of obesity.
We have medications to help opioid addiction and alcohol addiction. Why should this be any different?
i wonder how long patients will be able to tolerate it before some untoward side effect makes them stop. will this be another 6 month fad and then regain all the weight on the rebound? that is my suspicion. no one really loses weight and the drug company makes out great. i truly hope not but it has been a struggle with similarly intended medicines in the past
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I was talking to a urologist who treats obesity - and he says these drugs cause too much pancreatitis to be used at the rate that they are being used.
He uses b-HCG...says it works very well for weight loss. I had never heard of that.
GLP-1s and GI Side Effects: How to Manage Symptoms
Struggling with nausea or diarrhea on a GLP-1? Learn why these medications cause GI issues, which drugs have the fewest side effects, and tips for relief.
www.healthline.com
Your friend prescribes the b-HCG diet to his patients? Does he also have a flip phone and drive a car without power windows? I haven't heard of anyone actually recommending it in years.
The b-HCG diet doesn't work because of the HCG injections. It works because it stipulates that the patient follow a 500 calorie a day diet for several weeks.
Good point. Never thought of it this way.
Why is a urologist treating pancreatitis (<1% on the phase 3 studies of wegovy)? You'd think he be more worried about aki, another rare complication that shouldn't deter people from using them...
He's a shyster if he claims HCG does **** all
Pfizer has an ORAL version with similar weight-loss efficacy. It is in phase three clinical trial. For SDN investors who missed Novo Nordisk bandwagon, it may not be a bad idea to look into pfizer.
The stock price low, dividend good. Has a lot cash from covid vaccine to buy other companies, get RSV vaccine going, and now the weight loss drug.
The stock price low, dividend good. Has a lot cash from covid vaccine to buy other companies, get RSV vaccine going, and now the weight loss drug.
Meh, I've not been impressed with Rybelsus so far - for diabetes or weight loss.
After reading this thread, start to all these people on ozempic.
Just did one EGD this morning…. Young girl BMI 56, with 3 different meds for DM, one being ozempic 2mg two days ago.
Was like, nah, not gonna play. RSI…. Surgeon went in, can’t see shlt…. Came out.
Just did one EGD this morning…. Young girl BMI 56, with 3 different meds for DM, one being ozempic 2mg two days ago.
Was like, nah, not gonna play. RSI…. Surgeon went in, can’t see shlt…. Came out.
This is a problem. We need some practice guidelines or something definitive to guide practice in regards to holding these medications.
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So we’re asking everyone to be off of them for a week. Strict NPO 8 hours, including clear liquids.
May need to be even more aggressive, sounds like.
May need to be even more aggressive, sounds like.
I heard the asa is working on guidelines. Not sure when it’s coming out.
It's been a hot topic on the ASA Community forum.
Also…what’s everyone doing about the ERAS/ESR pre-op carb drink? Hold it as well?
Are Serious Anesthesia Risks of Semaglutide and Other GLP-1 Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia
Glucagon-like peptide (GLP-1) receptor agonists are an emerging and increasingly popular class of medications used for the treatment of type 2 diabetes mellitus and, more recently, obesity. Since the expansion of approved uses to include...
www.apsf.org
Hot off the press
Though doesn’t say what to do.
Not even remotely helpful.Are Serious Anesthesia Risks of Semaglutide and Other GLP-1 Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia
Glucagon-like peptide (GLP-1) receptor agonists are an emerging and increasingly popular class of medications used for the treatment of type 2 diabetes mellitus and, more recently, obesity. Since the expansion of approved uses to include...
Hot off the press
Though doesn’t say what to do.
Are Serious Anesthesia Risks of Semaglutide and Other GLP-1 Agonists Under-Recognized? Case Reports of Retained Solid Gastric Contents in Patients Undergoing Anesthesia
Glucagon-like peptide (GLP-1) receptor agonists are an emerging and increasingly popular class of medications used for the treatment of type 2 diabetes mellitus and, more recently, obesity. Since the expansion of approved uses to include...
Hot off the press
Though doesn’t say what to do.
Basically what we already know..
Thought multiple are working on oral forms?
Also totally unhelpful.
Wtf is this? A whole lot of nothingl-burger. And they published this? What a joke!
Would have thought one of these guidances would suggest gastric ultrasound!!
Ozempic Might Help You Drink and Smoke Less
Animal studies suggest GLP-1 drugs alter behaviors associated with reward and pleasure.
www.wsj.com
oh boy...everybody gonna be on it. pharmaceutical panacea
Unfortunately, without hard evidence, what are they supposed to say? It sucks, but we need more data.
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deleted87051
More indications.
Novo's Wegovy shows heart benefit alongside weight loss in trial
Wegovy maker Novo Nordisk said on Tuesday a large study had shown the highly effective obesity treatment also had a clear cardiovascular benefit, boosting the Danish company's hopes of moving beyond its image as a lifestyle drug.
We've known it has that benefit for diabetics for several years now. Not a shock it does it in non-diabetic obese people as well.More indications.
Novo's Wegovy shows heart benefit alongside weight loss in trial
Wegovy maker Novo Nordisk said on Tuesday a large study had shown the highly effective obesity treatment also had a clear cardiovascular benefit, boosting the Danish company's hopes of moving beyond its image as a lifestyle drug.www.reuters.com
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It’s almost as if diabetes, heart disease and obesity are in some way related.
You spelled gastroenterology wrong four whole times there.
D
deleted87051
FWIW I’ll tell another anecdote.
My brother in law has been on ozempic for a year now. He never ate very much and eats even less now. He’s 5’9” and has dropped from 230 to 180.
My brother in law has been on ozempic for a year now. He never ate very much and eats even less now. He’s 5’9” and has dropped from 230 to 180.
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I did 5 gastric ultrasounds for Mac cases today. Not as annoying as I thought it would be, but not everyone has a curvilinear probe and a sonosite lx
Tried it with a butterfly and a sonosite SiCU us machine not nearly as nice inages
Tried it with a butterfly and a sonosite SiCU us machine not nearly as nice inages
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Our private practice group has made it a policy that patient has to be off the drugs for at least 2 weeks for weekly dosing and clear liquid diet for at least 24 hours.
The gastric ultrasound I think would give me a false sense of security. Maybe others can comment. How reliable is it?
Unfortunately we have a few older Gi docs who still insist on colonoscopy first and then egds on doubles. Would like them to switch so we can abort if there’s food during egd
The gastric ultrasound I think would give me a false sense of security. Maybe others can comment. How reliable is it?
Unfortunately we have a few older Gi docs who still insist on colonoscopy first and then egds on doubles. Would like them to switch so we can abort if there’s food during egd
Arch Guillotti
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This is idiotic.
The experts seem to think (now) that it's highly validated and reliable imo. When I finished fellowship 10 years ago it was quasi experimental.
Above video posted because I liked it.
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That is problematic--these drugs are titrated to effect over a period of 3-4 months and the manufacturer states you have to start over if you are that far behind doses. They would have to have a PCP appointment to just figure out how to restart the med and a new Rx after surgery.
Wtf, I’ve never seen anyone do the colon first on a double. Is this done anywhere else? Can you tell them to do the upper first for safety purposes? I don’t see how it would matter to them.
D
deleted87051
Maybe they do it that way to avoid cancellations when they find a full stomach...
According to the experts, a negative gastric ultrasound has a 99% specificity.
It's stupid yes. But the rationale I've heard is that the colonoscopy is less stimulating.
D
deleted641888
I think it just depends. Are they using one scope or two?
D
deleted87051
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D
deleted1130227
It absolutely used to be.
D
deleted87051
I mean.. if the colono prep was excellent does it really matter?
D
deleted643396
I worked with one GI who did it this way. Frankly, I didn’t mind it. I was able to get the patient in a good plane of anesthesia and probably had less periods of apnea and/or gagging compared to doing the EGD first. I never thought about possible full stomach issues unless there were risk factors.
