Glycolysis-->how much ATP?

[skylark]

Cliffs pg 47 (chart) says during glycolysis, 2 NADH is made which makes 4 ATP. but at the bottom of the previous page, it states 1 NADH makes 3 ATP. Is there a step i am missing? so then what is the total amount of ATP made from glycolysis?

ALSO, how much ATP is made via oxidative phosphorylation? how many NADH and FADH2 went into oxidative phosphorylation to make those ATPs?

If you guys have been tested on the cycles, what kind of questions were they? did u need to know intermediates, or just overall goals of the pathways and resulting products?

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[PreDental88]

Cliffs pg 47 (chart) says during glycolysis, 2 NADH is made which makes 4 ATP. but at the bottom of the previous page, it states 1 NADH makes 3 ATP. Is there a step i am missing? so then what is the total amount of ATP made from glycolysis?
2 NADH from glycolysis makes 4 ATP total because glycolysis occurs in the cytosol, and it requires energy to transport NADH from the cytosol to the mitchondria, that's why NADH from glycolysis is worth less than NADH produced within the mitochondria. I hope that helps.

 

[Baylor2011]

In addition, glycolysis starts with 2ATP being used. Therefore the net is a little less than 2...but just remember "2", because the energy required to transfer NADH from the cytosol to the mitochondria for the citric acid cycle isn't important.

 

[Avery07]

PreDental88 hit the nail on the head about the lower ATP yield for glycolysis NADH.

Glycolysis produces 2 NADH and 2 ATP from substrate-level phosphorylation for one molecule of glucose.

So the answer could be very different from the type of question being asked..

Q: How many ATP from glycolysis in aerobic respiration?
A: Either 6 ATP (2 NADH = (2)2 ATP + 2 ATP) or 2 ATP depending on how you look at the question. Hopefully if this sort of question shows up on the DAT it will distinguish between substrate level and oxidative phosphorylation.

Q: How many ATP from glycolysis in anaerobic respiration?
A: 2 ATP

 

[gorrillaunit18]

There are 2 from glycolysis, however, there are 4 via substrate level phosphorylation. 👍

 

[Avery07]

There are 2 from glycolysis, however, there are 4 via substrate level phosphorylation. 👍

Ahahaha yet another take on o this question..

I never know what to say on the practice exams lol