These threads are always so interesting- often really skewed towards the upper end of the spectrum for salary. Saying "300k should be the absolute minimum" is all well and good, but the only places offering this in my area are really scummy for-profit hospitals with poor patient care and really high workloads.
If you're unattached and/or have a family/partner that's fine with moving anywhere in the country then you can hit this no problem, but it's also really reasonable to consider location, work/life balance, other benefits, interest in working with certain populations, etc.
Obviously I'd prefer if my job paid me 300k! But that's not the norm in my metro area, and I would not counsel that anyone looking in my area expect this. My souse and I both have local family, and I care more about being near to them than maximizing my earning potential. Once we're limited by that, it becomes a question of "settling" for somewhere in the low/mid-200s and liking my job, or chasing a higher salary for a predatory employer. Doesn't seem like this is the norm on this forum, but plenty of my residency classmates made similar calculations.