Guide on choosing NRTI

[Confusant]

Hey guys,

I'm studying the topic on AIDS at the moment. Do you have any particular guide that you use in the choosing of NRTI?

Cheers 🙂

 

[browneyes021]

here's the official guide from hivandhepatitis.com:

http://aidsinfo.nih.gov/contentfiles/AdultandAdolescentGL.pdf

 

[KARM12]

Hey guys,

I'm studying the topic on AIDS at the moment. Do you have any particular guide that you use in the choosing of NRTI?

Cheers 🙂

This is a bad question. It is very patient specific...depending on the patient's status, previous therapy, adherence, insurance... Overall we try to choose the least toxic regimen and one the patient will actually take.

 

[Confusant]

This is a bad question. It is very patient specific...depending on the patient's status, previous therapy, adherence, insurance... Overall we try to choose the least toxic regimen and one the patient will actually take.

I do agree with your sentiments here, KARM12. The learning condition, very very unfortunately, is heavily based on theory rather than practical experience. When it comes to oral examination, we are expected to cough out our drug of choice based on what has been specified in the guidelines.

 

[whitedc5]

There is no absolute standard in AIDs therapy as drug specfic side effects, patient medication profile, resistance testing, prior failing regimens, and patient adherence must be taken into account. There are guidelines for preferred treatment combinations but they may be highly variable depending on your patient. But generally, preferred NRTIs include FTC, 3TC, and TDF. The pregnancy preferred NRTI is ZDV. Along with this, you also want to take into account the adverse effects of particular NRTIs such as ddI and d4T.

 

[AC1997]

The learning condition, very very unfortunately, is heavily based on theory rather than practical experience.

There is no such thing as the formulary when it comes to academia.