Heinz bodies vs. Howell-Jolly bodies on blood smear

[SB100]

Is there a way to tell the difference between Heinz bodies and Howell-Jolly bodies if given a blood smear, without knowing the patient history?

---

Members don't see this ad.

 

[RySerr21]

Is there a way to tell the difference between Heinz bodies and Howell-Jolly bodies if given a blood smear, without knowing the patient history?

ehhhhhh........no? I cant think why that would ever happen though.

 

[21CentSouldier]

Is there a way to tell the difference between Heinz bodies and Howell-Jolly bodies if given a blood smear, without knowing the patient history?

Well, methylene blue can be used for Heinz. Aside from that, Heinz are proteinaceous material and Howell-Jolly's are nucleic material. So if there's a HE stain, shouldn't the Heinz end up as a more pinkish/reddish inclusions throughout and the Howell-Jolly's as purplish inclusions?