hemagluttin inhibition test

[cassieandcheeta]

Hi,

Could someone please explain how the hemagluttin inhibition test is done?

thanks so much,
cassie

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[SeventhSon]

it is a test looking for putative serum Ab to a hemagluttinating virus. In absence of antibody or low antibody concentration, virus will hemagluttinate RBCs together and they will form a lattice and stay in solution. In high antibody concentration, Ab will block the virus's hemagluttinating protein and RBC will sediment at the bottom.