Step I Heme questions

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vsmedic

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Hello,

Could someone please explain the following, having read Goljan and fa, these things are still not clear to me.

1. Is HMWK ( high molecular weight kallikrien) needed for the Intrinsic coagulation system? And what is kallikrien's purpose in general?

2. When does Factor 7 activate Factor 9, as it usually activates Factor 10?

3. Why is IgG given in ITP?

Thank's and good luck.
 
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