Hemorragic stroke

[Miracoli]

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A 73 years old pt with a history of DM and HTN presents with seizure and motor weakness. Noncontrast CT scan shows intraparenchymal bleeding with no mass shift. The pt is stable and the neurosurgeon tells the pt's family that no surgery is required and the clot will be dissolved with time. The types of cells involved in removing a blood clot from the brain are:
A. astrocytes
B. oligodendrocytes
C. microglias
D. ependymal cells
E. Schwann cells

 

[ulikedaggers]

Where are these questions coming from?

C would be my guess. Phagocytes.

 

[ChessMaster3000]

A 73 years old pt with a history of DM and HTN presents with seizure and motor weakness. Noncontrast CT scan shows intraparenchymal bleeding with no mass shift. The pt is stable and the neurosurgeon tells the pt's family that no surgery is required and the clot will be dissolved with time. The types of cells involved in removing a blood clot from the brain are:
A. astrocytes
B. oligodendrocytes
C. microglias
D. ependymal cells
E. Schwann cells

im going with A. I can never differentiate between the repair fxns of astrocytes and microglial

 

[AscorbicA]

C. Microglial cells for sure 👍

 

[Miracoli]

-

 

[Miracoli]

Where are these questions coming from?

.

They are not from U world, they are from Miracoli's world 🙂

 

[Transposony]

I can never differentiate between the repair fxns of astrocytes and microglial

Think of Astrocytes as "Maintenance crew" and Microglia (a macrophage) as "Trash collector" or "Pac-Man".

So once Microglia clears up the debris (blood clot), Astrocytes start the repair (fibrosis)

There is so much name calling for Macrophage 😀:

Foam cell: Atherosclerosis & Niemann-Pick disease
Foamy macrophage: Whipple disease
Gaucher cell: Gaucher disease
Heart failure cells: Pulmonary edema
Anitschkow cells: Rheumatic fever
Epitheloid/Giant cell: Granuloma

Also various things hide inside it😉:

HIV
Mycobacteria
Histoplasmosis
Leishmania

Hemosiderin
Heme
Lipofuscin
Iron (induced by Hepcidin)
Carbon
Silica

 

[ChessMaster3000]

Think of Astrocytes as "Maintenance crew" and Microglia (a macrophage) as "Trash collector" or "Pac-Man".

So once Microglia clears up the debris (blood clot), Astrocytes start the repair (fibrosis)

There is so much name calling for Macrophage 😀:

Foam cell: Atherosclerosis & Niemann-Pick disease
Foamy macrophage: Whipple disease
Gaucher cell: Gaucher disease
Heart failure cells: Pulmonary edema
Anitschkow cells: Rheumatic fever
Epitheloid/Giant cell: Granuloma

Also various things hide inside it😉:

HIV
Mycobacteria
Histoplasmosis
Leishmania

Hemosiderin
Heme
Lipofuscin
Iron (induced by Hepcidin)
Carbon
Silica

Aren't macrophages the reservoir for HIV even in a patient well controlled on haart?

 

[Transposony]

Aren't macrophages the reservoir for HIV even in a patient well controlled on haart?

Yes.

HIV Tat promotes cell survival in macrophages and in microglial cells

 

[Miracoli]

C is correct

Thank you transposony for the list.

Macrophages come in different flavors for every season and region

__________Names of macrophages in different tissues__________
•monocytes from BM to the blood and circulate 8 hours to mature--> migrate into tissues to become
macrophages
• macrophages--> in Blood, alveoli, intestines
• histiocytes--> in Connective tissue
• Kupffer cells--> in Liver
• Intraglomerular mesangial cells--> in Kidney
• microglia--> in CNS
• osteoclasts--> in Bone
• Alveolar macrophage(dust cells)--> in pulmonary alveolus of Lungs
• Langerhans cells--> in Skin and Mucosa

__________Names of macrophages in different different disease states__________
• Foam cell: Atherosclerosis & Niemann-Pick disease
http://www.nlm.nih.gov/medlineplus/ency/imagepages/1224.htm
• Foamy macrophage in the the lamina propria. : Whipple disease
• Gaucher cell: Gaucher disease
http://www.nlm.nih.gov/medlineplus/ency/imagepages/1450.htm
http://www.bravecommunity.com/App_Images/gaucher_cell_rv.gif
• Heart failure cells: Pulmonary edema
• Anitschkow cells: Rheumatic fever. Anitschkow cells are enlarged macrophages found within granulomas (called Aschoff bodies) associated with the disease
• Epitheloid/Giant cells: Granuloma