Hg

[drkooks]

---

Members do not see this ad.

1)Hemoglobin
increases in congestive heart disease and COPD

decrease in liver cirrhosis and hyperthyroid

why ?? please explain both cases.

2)sickle cell anemia decrease solubility of deoxy hemoglobin????
i am missing this point too

 

[skabbaraju]

1)Hemoglobin
increases in congestive heart disease and COPD

decrease in liver cirrhosis and hyperthyroid

why ?? please explain both cases.

2)sickle cell anemia decrease solubility of deoxy hemoglobin????
i am missing this point too

Both in CCF and COPD, there is reduced o2 supply to the organs and tissues due to which there would be a possible increased synthesis of erythropoietin and RBC production.

I am not sure how hemoglobin decreases in Cirrhosis and hyperthyroid.? I ll try to find out more on this.

In Sickle cell anemia, when there is a low concentration of o2, the HbS type polymerizes and is less soluble and less elastic causing obstruction of flow of RBC.