Horizant for RLS.

[pharmd2019*]

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Could someone please explain the reason why Horizant is not recommended for patients who must sleep during the daytime and remain awake at night? I can’t find any literature elaborating on this.

I have a patient who has been prescribed this, and she works nights as a CNA and sleeps during the day. I’m trying to decide if it’s the right drug for her, or if it should be changed to something different. Thanks!

 

[JustFillIt]

Gabapentin, I’m it’s many forms, is now considered the modern wonder drug. I recently questioned a physician for the diagnosis “for bipolar depression” and was told to let it be.

Anyways - I just let anything fly with gabapentin anymore. RLS? Sure why not..

Edit: I just realized I entirely missed the point of your post. I would guess that, since it’s such a new drug, it just was not studied that way and we all know how tightly drug manufacturers stick to the studies for their recommendations.

 

[RxPreceptor]

Maybe you are reading info/dose timing that applies to the general population's typical waking/sleeping hours (usual dose 5pm per lexicomp). Likely a matter of being studied in a population with regular hours and having a set dosing time in the monogram. I don't see why person couldn't just fit the dosing time to her schedule (ex) 5am).

 

[BidingMyTime]

Good question, I'm not sure why they would make a point to specifically say it's not recommended for people who sleep during the day. I can't think of any pharmacological reason why that would be so, unless they are assuming these people are switching back and forth from sleeping in the day to sleeping at night. Even so, as long as they are just taking it when they plan to have a full sleep, I don't know what the problem would be. If anyone ever runs into a Horizant rep, that would be an interesting question to ask.