hormones...

Discussion in 'MCAT Study Question Q&A' started by sweetpea2, Jun 17, 2008.

  1. sweetpea2

    Joined:
    Apr 21, 2008
    Messages:
    111
    Likes Received:
    0
    Status:
    Pre-Dental
    Can someone explain/give example of post transcription changing with pre and post hormones. Thanks
     
  2. Thread continues after this sponsor message. SDN Members do not see this ad.

  3. seraph524

    Joined:
    Sep 19, 2006
    Messages:
    1,588
    Likes Received:
    1
    Status:
    MD/PhD Student
    ??? Are you asking about hormones affecting post-transcriptional modifications? Hrm...I really can't think of an example!
     
  4. Kaustikos

    Kaustikos Archerize It

    Joined:
    Jan 18, 2008
    Messages:
    12,216
    Likes Received:
    4,153

    You mean post-transcriptional modification of hormones? The only example I can think of at the top of my head is Insulin. But I'm also thinking of post-translational modification. There are so many post-transcriptional/translational modifications that occur, though, that's specific to proteins, though.

    http://en.wikipedia.org/wiki/Insulin

    Click and let me know what you mean exactly from the explanation given.

    Also, did you mean that or how hormones regulate the production of products post-transcriptionally?
     
  5. sweetpea2

    Joined:
    Apr 21, 2008
    Messages:
    111
    Likes Received:
    0
    Status:
    Pre-Dental
    Yea i think insulin and pre insulin is an example. Thanks for the help!
     
  6. seraph524

    Joined:
    Sep 19, 2006
    Messages:
    1,588
    Likes Received:
    1
    Status:
    MD/PhD Student
    Remember that pre-insulin -> insulin is post-translational modification, not post-transcriptional.
     
  7. Kaustikos

    Kaustikos Archerize It

    Joined:
    Jan 18, 2008
    Messages:
    12,216
    Likes Received:
    4,153
    Yeah, that's what I remembered. Or that's the "main" insulin modification every text book talks about.
     
  8. minhaj

    minhaj Awesomeness Incarnate

    Joined:
    Dec 3, 2007
    Messages:
    201
    Likes Received:
    2
    Status:
    Medical Student
    would the changing of the digestive enzymes from zymogens to active proteins be considered as post-translational modification?
     
  9. seraph524

    Joined:
    Sep 19, 2006
    Messages:
    1,588
    Likes Received:
    1
    Status:
    MD/PhD Student
    Strictly speaking, thats defined as protein processing. Post-translational modification typically refers to modification of a peptide chain within the ER/golgi.
     

Share This Page